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GlyGen: Computational and Informatics Resources for Glycoscience
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data. GlyGen retrieves information from multiple international data sources and integrates and harmonizes this data. This web portal allows exploring this data and performing unique searches that cannot be executed in any of the integrated databases alone.
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Our Mission

Glycan Search

Search for glycan structures based on their chemical and structural properties.

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Protein Search

Search for proteins based on their sequences, accessions, and annotations.

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GlyGen Isoform Mapper

Map the amino acid and site position of a isoform protein sequence to the corresponding canonical isoform protein sequence.

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Super Search

Super search is a graphical interface to build queries across all GlyGen datasets.

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Site Search

Search for proteins based on their site and site annotations.

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Biomarker Search

Search for biomarkers based on their entity, condition, BEST role, and annotations.

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Composition Search

A search to find glycan(s) with specific monosaccharide composition in GlyGen.

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Structure Browser

Find glycan structures interactively by composition and topology via GNOme.

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List of Motifs

List of motifs includes detailed information and it's associated metadata.

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GlyGen Sand Box

The GlyGen Sandbox allows detailed exploration of glycan structure and biosynthesis.

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Glycan Structure Dictionary

The GSD provides a standardized list of glycan structure terms commonly described in publications.

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Quick Search

Quick Search provides multi-domain queries that are based on user requests.

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Protein BLAST

The GlyGen Protein BLAST allows to find regions of local similarity between protein sequences.

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GlyGen Mapper

ID mapping related to glycan, protein / glycoprotein and based on the user input.

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Data

Data from the different resources can be accessed and downloaded in resource-specific formats (e.g. CSV, RDF).

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API

A public web service API allows access to the datasets by retrieving requested data in JSON format.

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SPARQL

All datasets are RDFized using standard ontologies and made accessible via a SPARQL Endpoint.

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GlyGen is pleased to provide users with a variety of resources in glycobiology.

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Please provide feedback and suggestions to help us improve the GlyGen portal and make it more useful for the community.

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Glygen
GlyGen is supported and funded by the National Institute of General Medical Sciences under the grant # 1R24GM146616 - 01 and the National Institutes of Health Office of Strategic Coordination - The Common Fund under the grant # 1OT2OD032092.